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Detection of newly produced T and B lymphocytes by digital PCR in blood stored dry on nylon flocked swabs
BACKGROUND: A normal number of T-cell receptor excision circles (TRECs) and K-deleting recombination excision circles (KRECs) is considered a biomarker for adequate new T- and B-cell production. In newborns, detection of TRECs and KRECs by real time PCR from dried blood spotted on filter paper is us...
Autores principales: | Tessitore, Marion Vaglio, Sottini, Alessandra, Roccaro, Aldo M., Ghidini, Claudia, Bernardi, Simona, Martellosio, Giovanni, Serana, Federico, Imberti, Luisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381048/ https://www.ncbi.nlm.nih.gov/pubmed/28381232 http://dx.doi.org/10.1186/s12967-017-1169-9 |
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