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Head-to-head comparison of aggressive conventional therapy and three biological treatments and comparison of two de-escalation strategies in patients who respond to treatment: study protocol for a multicenter, randomized, open-label, blinded-assessor, phase 4 study

BACKGROUND: New targeted therapies and improved treatment strategies have dramatically improved the outcomes of patients with rheumatoid arthritis (RA). However, it is unknown whether different early aggressive interventions can induce stable remission or a low-active disease state that can be maint...

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Detalles Bibliográficos
Autores principales: Glinatsi, Daniel, Heiberg, Marte S., Rudin, Anna, Nordström, Dan, Haavardsholm, Espen A., Gudbjornsson, Bjorn, Østergaard, Mikkel, Uhlig, Till, Grondal, Gerdur, Hørslev-Petersen, Kim, van Vollenhoven, Ronald, Hetland, Merete L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381054/
https://www.ncbi.nlm.nih.gov/pubmed/28376912
http://dx.doi.org/10.1186/s13063-017-1891-x