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Grape seed-derived procyanidins alleviate gout pain via NLRP3 inflammasome suppression
BACKGROUND: Gout is one of the common inflammatory arthritis which affects many people for inflicting unbearable pain. Macrophage-mediated inflammation plays an important role in gout. The uptake of monosodium urate (MSU) crystals by macrophages can lead to activation of NOD-like receptors containin...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381065/ https://www.ncbi.nlm.nih.gov/pubmed/28376889 http://dx.doi.org/10.1186/s12974-017-0849-y |