Chemical inhibition reveals differential requirements of signaling pathways in kras(V12)- and Myc-induced liver tumors in transgenic zebrafish

Previously we have generated inducible liver tumor models by transgenic expression of an oncogene and robust tumorigenesis can be rapidly induced by activation of the oncogene in both juvenile and adult fish. In the present study, we aimed at chemical intervention of tumorigenesis for understanding...

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Detalles Bibliográficos
Autores principales: Yan, Chuan, Yang, Qiqi, Huo, Xiaojing, Li, Hankun, Zhou, Li, Gong, Zhiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381109/
https://www.ncbi.nlm.nih.gov/pubmed/28378824
http://dx.doi.org/10.1038/srep45796

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381109/
https://www.ncbi.nlm.nih.gov/pubmed/28378824
http://dx.doi.org/10.1038/srep45796

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