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On-chip in vitro cell-network pre-clinical cardiac toxicity using spatiotemporal human cardiomyocyte measurement on a chip

To overcome the limitations and misjudgments of conventional prediction of arrhythmic cardiotoxicity, we have developed an on-chip in vitro predictive cardiotoxicity assay using cardiomyocytes derived from human stem cells employing a constructive spatiotemporal two step measurement of fluctuation (...

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Detalles Bibliográficos
Autores principales: Kaneko, Tomoyuki, Nomura, Fumimasa, Hamada, Tomoyo, Abe, Yasuyuki, Takamori, Hideo, Sakakura, Tomoko, Takasuna, Kiyoshi, Sanbuissho, Atsushi, Hyllner, Johan, Sartipy, Peter, Yasuda, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381194/
https://www.ncbi.nlm.nih.gov/pubmed/24751527
http://dx.doi.org/10.1038/srep04670