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Analysis of MTHFR, CBS, Glutathione, Taurine, and Hydrogen Sulfide Levels in Retinas of Hyperhomocysteinemic Mice

PURPOSE: Hyperhomocysteinemia (Hhcy) is implicated in certain retinal neurovascular diseases, although whether it is causative remains uncertain. In isolated ganglion cells (GCs), mild Hhcy induces profound death, whereas retinal phenotypes in Hhcy mice caused by mutations in remethylation (methylen...

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Detalles Bibliográficos
Autores principales: Cui, Xuezhi, Navneet, Soumya, Wang, Jing, Roon, Penny, Chen, Wei, Xian, Ming, Smith, Sylvia B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381329/
https://www.ncbi.nlm.nih.gov/pubmed/28384716
http://dx.doi.org/10.1167/iovs.16-21247