Toll-Like Receptors 2, -3 and -4 Prime Microglia but not Astrocytes Across Central Nervous System Regions for ATP-Dependent Interleukin-1β Release

Interleukin-1β (IL-1β) is a crucial mediator in the pathogenesis of inflammatory diseases at the periphery and in the central nervous system (CNS). Produced as an unprocessed and inactive pro-form which accumulates intracellularly, release of the processed cytokine is strongly promoted by ATP acting...

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Detalles Bibliográficos
Autores principales: Facci, Laura, Barbierato, Massimo, Marinelli, Carla, Argentini, Carla, Skaper, Stephen D., Giusti, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381369/
https://www.ncbi.nlm.nih.gov/pubmed/25351234
http://dx.doi.org/10.1038/srep06824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381369/
https://www.ncbi.nlm.nih.gov/pubmed/25351234
http://dx.doi.org/10.1038/srep06824

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