Yokukansan, a Kampo medicine, prevents the development of morphine tolerance through the inhibition of spinal glial cell activation in rats

BACKGROUND: Animal models have shown that glial cells (microglia and astrocytes) in the spinal cord undergo activation following peripheral injury associated with chronic pain, suggesting the involvement of these cells in pain diseases. We have previously reported that Yokukansan (YKS), a Japanese t...

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Detalles Bibliográficos
Autores principales: Takemoto, Mariko, Sunagawa, Masataka, Okada, Mayumi, Ikemoto, Hideshi, Suga, Hiroki, Katayama, Ayami, Otake, Hiroshi, Hisamitsu, Tadashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381433/
https://www.ncbi.nlm.nih.gov/pubmed/28462096
http://dx.doi.org/10.1016/j.imr.2015.12.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381433/
https://www.ncbi.nlm.nih.gov/pubmed/28462096
http://dx.doi.org/10.1016/j.imr.2015.12.003

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