Cargando…
Standard Codon Substitution Models Overestimate Purifying Selection for Nonstationary Data
Estimation of natural selection on protein-coding sequences is a key comparative genomics approach for de novo prediction of lineage-specific adaptations. Selective pressure is measured on a per-gene basis by comparing the rate of nonsynonymous substitutions to the rate of synonymous substitutions....
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381540/ https://www.ncbi.nlm.nih.gov/pubmed/28175284 http://dx.doi.org/10.1093/gbe/evw308 |