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A Nonsynonymous SNP Catalog of Mycobacterium tuberculosis Virulence Genes and Its Use for Detecting New Potentially Virulent Sublineages

Mycobacterium tuberculosis is divided into several distinct lineages, and various genetic markers such as IS-elements, VNTR, and SNPs are used for lineage identification. We propose an M. tuberculosis classification approach based on functional polymorphisms in virulence genes. An M. tuberculosis vi...

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Detalles Bibliográficos
Autores principales: Mikheecheva, Natalya E., Zaychikova, Marina V., Melerzanov, Alexander V., Danilenko, Valery N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381574/
https://www.ncbi.nlm.nih.gov/pubmed/28338924
http://dx.doi.org/10.1093/gbe/evx053