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Construction and characteristics of an E-cadherin-related three-dimensional suspension growth model of ovarian cancer

Ovarian cancer is the deadliest of all gynecologic malignancies. Metastatic ovarian cancer cells exist mainly in the form of multi-cellular spheroids (MCSs) in the ascites of patients with advanced ovarian cancer. We hypothesized that E-cadherin, as an important cell-adhesion molecule, might play an...

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Detalles Bibliográficos
Autores principales: Xu, Shan, Yang, Ya'nan, Dong, Lingling, Qiu, Wenlong, Yang, Lu, Wang, Xiuwen, Liu, Lian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381612/
https://www.ncbi.nlm.nih.gov/pubmed/25008268
http://dx.doi.org/10.1038/srep05646