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A design principle underlying the paradoxical roles of E3 ubiquitin ligases

E3 ubiquitin ligases are important cellular components that determine the specificity of proteolysis in the ubiquitin-proteasome system. However, an increasing number of studies have indicated that E3 ubiquitin ligases also participate in transcription. Intrigued by the apparently paradoxical functi...

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Detalles Bibliográficos
Autores principales: Lee, Daewon, Kim, Minjin, Cho, Kwang-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381699/
https://www.ncbi.nlm.nih.gov/pubmed/24994517
http://dx.doi.org/10.1038/srep05573