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Plasticity of Listeriolysin O Pores and its Regulation by pH and Unique Histidine

Pore formation of cellular membranes is an ancient mechanism of bacterial pathogenesis that allows efficient damaging of target cells. Several mechanisms have been described, however, relatively little is known about the assembly and properties of pores. Listeriolysin O (LLO) is a pH-regulated chole...

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Detalles Bibliográficos
Autores principales: Podobnik, Marjetka, Marchioretto, Marta, Zanetti, Manuela, Bavdek, Andrej, Kisovec, Matic, Cajnko, Miša Mojca, Lunelli, Lorenzo, Serra, Mauro Dalla, Anderluh, Gregor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381700/
https://www.ncbi.nlm.nih.gov/pubmed/25854672
http://dx.doi.org/10.1038/srep09623