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Rab27A Regulates Transport of Cell Surface Receptors Modulating Multinucleation and Lysosome-Related Organelles in Osteoclasts

Rab27A regulates transport of lysosome-related organelles (LROs) and release of secretory granules in various types of cells. Here, we identified up-regulation of Rab27A during differentiation of osteoclasts (OCLs) from bone-marrow macrophages (BMMs), by DNA microarray analysis. Rab27A deficiency in...

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Detalles Bibliográficos
Autores principales: Shimada-Sugawara, Megumi, Sakai, Eiko, Okamoto, Kuniaki, Fukuda, Mitsunori, Izumi, Tetsuro, Yoshida, Noriaki, Tsukuba, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381753/
https://www.ncbi.nlm.nih.gov/pubmed/25882854
http://dx.doi.org/10.1038/srep09620