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Rab27A Regulates Transport of Cell Surface Receptors Modulating Multinucleation and Lysosome-Related Organelles in Osteoclasts
Rab27A regulates transport of lysosome-related organelles (LROs) and release of secretory granules in various types of cells. Here, we identified up-regulation of Rab27A during differentiation of osteoclasts (OCLs) from bone-marrow macrophages (BMMs), by DNA microarray analysis. Rab27A deficiency in...
Autores principales: | Shimada-Sugawara, Megumi, Sakai, Eiko, Okamoto, Kuniaki, Fukuda, Mitsunori, Izumi, Tetsuro, Yoshida, Noriaki, Tsukuba, Takayuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381753/ https://www.ncbi.nlm.nih.gov/pubmed/25882854 http://dx.doi.org/10.1038/srep09620 |
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