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Simple agarose micro-confinement array and machine-learning-based classification for analyzing the patterned differentiation of mesenchymal stem cells

The geometrical confinement of small cell colonies gives differential cues to cells sitting at the periphery versus the core. To utilize this effect, for example to create spatially graded differentiation patterns of human mesenchymal stem cells (hMSCs) in vitro or to investigate underpinning mechan...

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Detalles Bibliográficos
Autores principales: Tanaka, Nobuyuki, Yamashita, Tadahiro, Sato, Asako, Vogel, Viola, Tanaka, Yo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381775/
https://www.ncbi.nlm.nih.gov/pubmed/28380036
http://dx.doi.org/10.1371/journal.pone.0173647