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Mouse fitness measures reveal incomplete functional redundancy of Hox paralogous group 1 proteins
Here we assess the fitness consequences of the replacement of the Hoxa1 coding region with its paralog Hoxb1 in mice (Mus musculus) residing in semi-natural enclosures. Previously, this Hoxa1(B1) swap was reported as resulting in no discernible embryonic or physiological phenotype (i.e., functionall...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381901/ https://www.ncbi.nlm.nih.gov/pubmed/28380068 http://dx.doi.org/10.1371/journal.pone.0174975 |