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Engineering cancer stem-like cells from normal human lung epithelial cells

It has been proposed that a subpopulation of tumour cells with stem cell-like characteristics, known as cancer stem cells (CSCs), drives tumour initiation and generates tumour heterogeneity, thus leading to cancer metastasis, recurrence, and drug resistance. Although there has been substantial progr...

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Detalles Bibliográficos
Autores principales: Sasai, Ken, Takao-Rikitsu, Etsuko, Sukezane, Taiko, Yanagita, Emmy, Nakagawa, Harumi, Itoh-Yagi, Machiko, Izumi, Yukina, Itoh, Tomoo, Akagi, Tsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381922/
https://www.ncbi.nlm.nih.gov/pubmed/28380052
http://dx.doi.org/10.1371/journal.pone.0175147