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Evolutionary dynamics of CRISPR gene drives

The alteration of wild populations has been discussed as a solution to a number of humanity’s most pressing ecological and public health concerns. Enabled by the recent revolution in genome editing, clustered regularly interspaced short palindromic repeats (CRISPR) gene drives—selfish genetic elemen...

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Detalles Bibliográficos
Autores principales: Noble, Charleston, Olejarz, Jason, Esvelt, Kevin M., Church, George M., Nowak, Martin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381957/
https://www.ncbi.nlm.nih.gov/pubmed/28435878
http://dx.doi.org/10.1126/sciadv.1601964