In Vitro Effects of Lead on Gene Expression in Neural Stem Cells and Associations between Up-regulated Genes and Cognitive Scores in Children

BACKGROUND: Lead (Pb) adversely affects neurodevelopment in children. Neural stem cells (NSCs) play an essential role in shaping the developing brain, yet little is known about how Pb perturbs NSC functions and whether such perturbation contributes to impaired neurodevelopment. OBJECTIVES: We aimed...

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Detalles Bibliográficos
Autores principales: Wagner, Peter J., Park, Hae-Ryung, Wang, Zhaoxi, Kirchner, Rory, Wei, Yongyue, Su, Li, Stanfield, Kirstie, Guilarte, Tomas R., Wright, Robert O., Christiani, David C., Lu, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381979/
https://www.ncbi.nlm.nih.gov/pubmed/27562236
http://dx.doi.org/10.1289/EHP265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381979/
https://www.ncbi.nlm.nih.gov/pubmed/27562236
http://dx.doi.org/10.1289/EHP265

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