Systemic klotho is associated with KLOTHO variation and predicts intrinsic cortical connectivity in healthy human aging

Cognitive decline is a major biomedical challenge as the global population ages. Elevated levels of the longevity factor klotho suppress aging, enhance cognition, and promote synaptic plasticity and neural resilience against aging and Alzheimer’s disease (AD)-related pathogenic proteins. Here, we ex...

Descripción completa

Detalles Bibliográficos
Autores principales: Yokoyama, Jennifer S., Marx, Gabe, Brown, Jesse A., Bonham, Luke W., Wang, Dan, Coppola, Giovanni, Seeley, William W., Rosen, Howard J., Miller, Bruce L., Kramer, Joel H., Dubal, Dena B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
SI: Resilience/Reserve in AD
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382127/
https://www.ncbi.nlm.nih.gov/pubmed/27714549
http://dx.doi.org/10.1007/s11682-016-9598-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382127/
https://www.ncbi.nlm.nih.gov/pubmed/27714549
http://dx.doi.org/10.1007/s11682-016-9598-2

Ejemplares similares