A Novel Regulator of Activation-Induced Cytidine Deaminase/APOBECs in Immunity and Cancer: Schrödinger’s CATalytic Pocket

Activation-induced cytidine deaminase (AID) and its relative APOBEC3 cytidine deaminases boost immune response by mutating immune or viral genes. Because of their genome-mutating activities, AID/APOBECs are also drivers of tumorigenesis. Due to highly charged surfaces, extensive non-specific protein...

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Detalles Bibliográficos
Autores principales: King, Justin J., Larijani, Mani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382155/
https://www.ncbi.nlm.nih.gov/pubmed/28439266
http://dx.doi.org/10.3389/fimmu.2017.00351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382155/
https://www.ncbi.nlm.nih.gov/pubmed/28439266
http://dx.doi.org/10.3389/fimmu.2017.00351

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