Protein Quality Control by Molecular Chaperones in Neurodegeneration

Protein homeostasis (proteostasis) requires the timely degradation of misfolded proteins and their aggregates by protein quality control (PQC), of which molecular chaperones are an essential component. Compared with other cell types, PQC in neurons is particularly challenging because they have a uni...

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Detalles Bibliográficos
Autores principales: Ciechanover, Aaron, Kwon, Yong Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382173/
https://www.ncbi.nlm.nih.gov/pubmed/28428740
http://dx.doi.org/10.3389/fnins.2017.00185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382173/
https://www.ncbi.nlm.nih.gov/pubmed/28428740
http://dx.doi.org/10.3389/fnins.2017.00185

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