Cargando…

Physiological Functions of the Cellular Prion Protein

The prion protein, PrP(C), is a small, cell-surface glycoprotein notable primarily for its critical role in pathogenesis of the neurodegenerative disorders known as prion diseases. A hallmark of prion diseases is the conversion of PrP(C) into an abnormally folded isoform, which provides a template f...

Descripción completa

Detalles Bibliográficos
Autores principales: Castle, Andrew R., Gill, Andrew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382174/
https://www.ncbi.nlm.nih.gov/pubmed/28428956
http://dx.doi.org/10.3389/fmolb.2017.00019