Desensitizing Mitochondrial Permeability Transition by ERK-Cyclophilin D Axis Contributes to the Neuroprotective Effect of Gallic Acid against Cerebral Ischemia/Reperfusion Injury

Ischemic stroke is a devastating disease with complex pathophysiology. Much evidence confirms that opening of the mitochondrial permeability transition pore (MPTP) is related with mitochondrial dysfunction to apoptosis in ischemic stroke, thus elucidating its signaling mechanism and screening novel...

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Detalles Bibliográficos
Autores principales: Sun, Jing, Ren, Da-Dui, Wan, Jin-Yi, Chen, Chen, Chen, Dong, Yang, Huan, Feng, Chun-Lai, Gao, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382198/
https://www.ncbi.nlm.nih.gov/pubmed/28428752
http://dx.doi.org/10.3389/fphar.2017.00184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382198/
https://www.ncbi.nlm.nih.gov/pubmed/28428752
http://dx.doi.org/10.3389/fphar.2017.00184

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