Pharmacological Analysis of the Anti-epileptic Mechanisms of Fenfluramine in scn1a Mutant Zebrafish

Dravet syndrome (DS) is a genetic encephalopathy that is characterized by severe seizures and prominent co-morbidities (e.g., physical, intellectual disabilities). More than 85% of the DS patients carry an SCN1A mutation (sodium channel, voltage gated, type I alpha subunit). Although numerous anti-e...

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Detalles Bibliográficos
Autores principales: Sourbron, Jo, Smolders, Ilse, de Witte, Peter, Lagae, Lieven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382218/
https://www.ncbi.nlm.nih.gov/pubmed/28428755
http://dx.doi.org/10.3389/fphar.2017.00191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382218/
https://www.ncbi.nlm.nih.gov/pubmed/28428755
http://dx.doi.org/10.3389/fphar.2017.00191

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