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Phosphoproteomics of Primary Cells Reveals Druggable Kinase Signatures in Ovarian Cancer

Our understanding of the molecular determinants of cancer is still inadequate because of cancer heterogeneity. Here, using epithelial ovarian cancer (EOC) as a model system, we analyzed a minute amount of patient-derived epithelial cells from either healthy or cancerous tissues by single-shot mass-s...

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Detalles Bibliográficos
Autores principales: Francavilla, Chiara, Lupia, Michela, Tsafou, Kalliopi, Villa, Alessandra, Kowalczyk, Katarzyna, Rakownikow Jersie-Christensen, Rosa, Bertalot, Giovanni, Confalonieri, Stefano, Brunak, Søren, Jensen, Lars J., Cavallaro, Ugo, Olsen, Jesper V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382236/
https://www.ncbi.nlm.nih.gov/pubmed/28355574
http://dx.doi.org/10.1016/j.celrep.2017.03.015