Liver-Specific Activation of AMPK Prevents Steatosis on a High-Fructose Diet

AMP-activated protein kinase (AMPK) plays a key role in integrating metabolic pathways in response to energy demand. We identified a mutation in the γ1 subunit (γ1(D316A)) that leads to activation of AMPK. We generated mice with this mutation to study the effect of chronic liver-specific activation...

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Detalles Bibliográficos
Autores principales: Woods, Angela, Williams, Jennet R., Muckett, Phillip J., Mayer, Faith V., Liljevald, Maria, Bohlooly-Y, Mohammad, Carling, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382239/
https://www.ncbi.nlm.nih.gov/pubmed/28355557
http://dx.doi.org/10.1016/j.celrep.2017.03.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382239/
https://www.ncbi.nlm.nih.gov/pubmed/28355557
http://dx.doi.org/10.1016/j.celrep.2017.03.011

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