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Structure and antagonism of the receptor complex mediated by human TSLP in allergy and asthma

The pro-inflammatory cytokine thymic stromal lymphopoietin (TSLP) is pivotal to the pathophysiology of widespread allergic diseases mediated by type 2 helper T cell (Th2) responses, including asthma and atopic dermatitis. The emergence of human TSLP as a clinical target against asthma calls for maxi...

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Detalles Bibliográficos
Autores principales: Verstraete, Kenneth, Peelman, Frank, Braun, Harald, Lopez, Juan, Van Rompaey, Dries, Dansercoer, Ann, Vandenberghe, Isabel, Pauwels, Kris, Tavernier, Jan, Lambrecht, Bart N., Hammad, Hamida, De Winter, Hans, Beyaert, Rudi, Lippens, Guy, Savvides, Savvas N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382266/
https://www.ncbi.nlm.nih.gov/pubmed/28368013
http://dx.doi.org/10.1038/ncomms14937