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Src family kinases Fyn and Lyn are constitutively activated and mediate plasmacytoid dendritic cell responses
Plasmacytoid dendritic cells (pDC) are type I interferon-producing cells with critical functions in a number of human illnesses; however, their molecular regulation is incompletely understood. Here we show the role of Src family kinases (SFK) in mouse and human pDCs. pDCs express Fyn and Lyn and the...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382270/ https://www.ncbi.nlm.nih.gov/pubmed/28368000 http://dx.doi.org/10.1038/ncomms14830 |