Cargando…

Src family kinases Fyn and Lyn are constitutively activated and mediate plasmacytoid dendritic cell responses

Plasmacytoid dendritic cells (pDC) are type I interferon-producing cells with critical functions in a number of human illnesses; however, their molecular regulation is incompletely understood. Here we show the role of Src family kinases (SFK) in mouse and human pDCs. pDCs express Fyn and Lyn and the...

Descripción completa

Detalles Bibliográficos
Autores principales: Dallari, S., Macal, M., Loureiro, M. E., Jo, Y., Swanson, L., Hesser, C., Ghosh, P., Zuniga, E. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382270/
https://www.ncbi.nlm.nih.gov/pubmed/28368000
http://dx.doi.org/10.1038/ncomms14830