IL-33 contributes to sepsis-induced long-term immunosuppression by expanding the regulatory T cell population

Patients who survive sepsis can develop long-term immune dysfunction, with expansion of the regulatory T (Treg) cell population. However, how Treg cells proliferate in these patients is not clear. Here we show that IL-33 has a major function in the induction of this immunosuppression. Mice deficient...

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Detalles Bibliográficos
Autores principales: Nascimento, Daniele C., Melo, Paulo H., Piñeros, Annie R., Ferreira, Raphael G., Colón, David F., Donate, Paula B., Castanheira, Fernanda V., Gozzi, Aline, Czaikoski, Paula G., Niedbala, Wanda, Borges, Marcos C., Zamboni, Dario S., Liew, Foo Y., Cunha, Fernando Q., Alves-Filho, Jose C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382289/
https://www.ncbi.nlm.nih.gov/pubmed/28374774
http://dx.doi.org/10.1038/ncomms14919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382289/
https://www.ncbi.nlm.nih.gov/pubmed/28374774
http://dx.doi.org/10.1038/ncomms14919

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