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Genetic silencing of olivocerebellar synapses causes dystonia-like behaviour in mice

Theories of cerebellar function place the inferior olive to cerebellum connection at the centre of motor behaviour. One possible implication of this is that disruption of olivocerebellar signalling could play a major role in initiating motor disease. To test this, we devised a mouse genetics approac...

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Detalles Bibliográficos
Autores principales: White, Joshua J., Sillitoe, Roy V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382291/
https://www.ncbi.nlm.nih.gov/pubmed/28374839
http://dx.doi.org/10.1038/ncomms14912