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Decreased Levels of Foldase and Chaperone Proteins Are Associated with an Early-Onset Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by a progressive upper and lower motor neuron degeneration. One of the peculiar clinical characteristics of ALS is the wide distribution in age of onset, which is probably caused by different combinations of intri...

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Detalles Bibliográficos
Autores principales: Filareti, Melania, Luotti, Silvia, Pasetto, Laura, Pignataro, Mauro, Paolella, Katia, Messina, Paolo, Pupillo, Elisabetta, Filosto, Massimiliano, Lunetta, Christian, Mandrioli, Jessica, Fuda, Giuseppe, Calvo, Andrea, Chiò, Adriano, Corbo, Massimo, Bendotti, Caterina, Beghi, Ettore, Bonetto, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382314/
https://www.ncbi.nlm.nih.gov/pubmed/28428745
http://dx.doi.org/10.3389/fnmol.2017.00099