Precise through-space control of an abiotic electrophilic aromatic substitution reaction

Nature has evolved selective enzymes for the efficient biosynthesis of complex products. This exceptional ability stems from adapted enzymatic pockets, which geometrically constrain reactants and stabilize specific reactive intermediates by placing electron-donating/accepting residues nearby. Here w...

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Detalles Bibliográficos
Autores principales: Murphy, Kyle E., Bocanegra, Jessica L., Liu, Xiaoxi, Chau, H.-Y. Katharine, Lee, Patrick C., Li, Jianing, Schneebeli, Severin T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382318/
https://www.ncbi.nlm.nih.gov/pubmed/28378788
http://dx.doi.org/10.1038/ncomms14840

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382318/
https://www.ncbi.nlm.nih.gov/pubmed/28378788
http://dx.doi.org/10.1038/ncomms14840

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