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EcR recruits dMi-2 and increases efficiency of dMi-2-mediated remodelling to constrain transcription of hormone-regulated genes

Gene regulation by steroid hormones plays important roles in health and disease. In Drosophila, the hormone ecdysone governs transitions between key developmental stages. Ecdysone-regulated genes are bound by a heterodimer of ecdysone receptor (EcR) and Ultraspiracle. According to the bimodal switch...

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Detalles Bibliográficos
Autores principales: Kreher, Judith, Kovač, Kristina, Bouazoune, Karim, Mačinković, Igor, Ernst, Anna Luise, Engelen, Erik, Pahl, Roman, Finkernagel, Florian, Murawska, Magdalena, Ullah, Ikram, Brehm, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382322/
https://www.ncbi.nlm.nih.gov/pubmed/28378812
http://dx.doi.org/10.1038/ncomms14806