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Interaction between prenatal pesticide exposure and a common polymorphism in the PON1 gene on DNA methylation in genes associated with cardio-metabolic disease risk—an exploratory study

BACKGROUND: Prenatal environmental conditions may influence disease risk in later life. We previously found a gene-environment interaction between the paraoxonase 1 (PON1) Q192R genotype and prenatal pesticide exposure leading to an adverse cardio-metabolic risk profile at school age. However, the m...

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Detalles Bibliográficos
Autores principales: Declerck, Ken, Remy, Sylvie, Wohlfahrt-Veje, Christine, Main, Katharina M., Van Camp, Guy, Schoeters, Greet, Vanden Berghe, Wim, Andersen, Helle R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382380/
https://www.ncbi.nlm.nih.gov/pubmed/28396702
http://dx.doi.org/10.1186/s13148-017-0336-4