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Control of immune cell entry through the tumour vasculature: a missing link in optimising melanoma immunotherapy?

Metastatic melanoma remains a fatal disease to many worldwide, even after the breakthrough introduction of targeted therapies such as BRAF inhibitors and immune checkpoint blockade therapies such as CTLA-4 and PD-1 inhibitors. With advances in our understanding of this disease, as well as the increa...

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Detalles Bibliográficos
Autores principales: Tan, Lih Yin, Martini, Carmela, Fridlender, Zvi G, Bonder, Claudine S, Brown, Michael P, Ebert, Lisa M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382436/
https://www.ncbi.nlm.nih.gov/pubmed/28435677
http://dx.doi.org/10.1038/cti.2017.7