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Genotoxicity and acute and subchronic toxicity studies of a bioactive polyoxometalate in Wistar rats

BACKGROUND: Cs(2)K(4)Na [SiW(9)Nb(3)O(40)] (POM93) is a novel broad-spectrum antiviral agent with high activity, high stability, and low toxicity in vitro. Most toxicity studies for POM93 have been performed in cultured cell lines rather than in animals. Like other POMs, there is a lack of evidence...

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Detalles Bibliográficos
Autores principales: Qu, Xiaofeng, Xu, Kun, Zhao, Chao, Song, Xiuling, Li, Jinhua, Li, Li, Nie, Wei, Bao, Hao, Wang, Juan, Niu, Fenglan, Li, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382445/
https://www.ncbi.nlm.nih.gov/pubmed/28381296
http://dx.doi.org/10.1186/s40360-017-0133-x