Five lipoxygenase hypomethylation mediates the homocysteine effect on Alzheimer’s phenotype

Environmental and genetic risk factors are implicated in the pathogenesis of Alzheimer’s disease (AD). However, how they interact and influence its pathogenesis remains to be investigated. High level of homocysteine (Hcy) is an AD risk factor and associates with an up-regulation of the ALOX5 gene. I...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Jian-Guo, Barrero, Carlos, Merali, Salim, Praticò, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382538/
https://www.ncbi.nlm.nih.gov/pubmed/28383037
http://dx.doi.org/10.1038/srep46002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382538/
https://www.ncbi.nlm.nih.gov/pubmed/28383037
http://dx.doi.org/10.1038/srep46002

Ejemplares similares