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Connecting myelin-related and synaptic dysfunction in schizophrenia with SNP-rich gene expression hubs

Combining genome-wide mapping of SNP-rich regions in schizophrenics and gene expression data in all brain compartments across the human life span revealed that genes with promoters most frequently mutated in schizophrenia are expression hubs interacting with far more genes than the rest of the genom...

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Detalles Bibliográficos
Autor principal: Hegyi, Hedi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382542/
https://www.ncbi.nlm.nih.gov/pubmed/28382934
http://dx.doi.org/10.1038/srep45494