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Next-generation sequencing enables the discovery of more diverse positive clones from a phage-displayed antibody library

Phage display technology provides a powerful tool to screen a library for a binding molecule via an enrichment process. It has been adopted as a critical technology in the development of therapeutic antibodies. However, a major drawback of phage display technology is that because the degree of the e...

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Detalles Bibliográficos
Autores principales: Yang, Wonjun, Yoon, Aerin, Lee, Sanghoon, Kim, Soohyun, Han, Jungwon, Chung, Junho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382563/
https://www.ncbi.nlm.nih.gov/pubmed/28336957
http://dx.doi.org/10.1038/emm.2017.22