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Tribbles in the 21st Century: The Evolving Roles of Tribbles Pseudokinases in Biology and Disease

The Tribbles (TRIB) pseudokinases control multiple aspects of eukaryotic cell biology and evolved unique features distinguishing them from all other protein kinases. The atypical pseudokinase domain retains a regulated binding platform for substrates, which are ubiquitinated by context-specific E3 l...

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Detalles Bibliográficos
Autores principales: Eyers, Patrick A., Keeshan, Karen, Kannan, Natarajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Publishers 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382568/
https://www.ncbi.nlm.nih.gov/pubmed/27908682
http://dx.doi.org/10.1016/j.tcb.2016.11.002