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Tribbles in the 21st Century: The Evolving Roles of Tribbles Pseudokinases in Biology and Disease
The Tribbles (TRIB) pseudokinases control multiple aspects of eukaryotic cell biology and evolved unique features distinguishing them from all other protein kinases. The atypical pseudokinase domain retains a regulated binding platform for substrates, which are ubiquitinated by context-specific E3 l...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier Science Publishers
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382568/ https://www.ncbi.nlm.nih.gov/pubmed/27908682 http://dx.doi.org/10.1016/j.tcb.2016.11.002 |