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High Salt Intake Augments Excitability of PVN Neurons in Rats: Role of the Endoplasmic Reticulum Ca(2+) Store

High salt (HS) intake sensitizes central autonomic circuitry leading to sympathoexcitation. However, its underlying mechanisms are not fully understood. We hypothesized that inhibition of PVN endoplasmic reticulum (ER) Ca(2+) store function would augment PVN neuronal excitability and sympathetic ner...

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Detalles Bibliográficos
Autores principales: Larson, Robert A., Chapp, Andrew D., Gui, Le, Huber, Michael J., Cheng, Zixi Jack, Shan, Zhiying, Chen, Qing-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382644/
https://www.ncbi.nlm.nih.gov/pubmed/28428739
http://dx.doi.org/10.3389/fnins.2017.00182