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p38α MAPK regulates proliferation and differentiation of osteoclast progenitors and bone remodeling in an aging-dependent manner

Bone mass is determined by the balance between bone formation, carried out by mesenchymal stem cell-derived osteoblasts, and bone resorption, carried out by monocyte-derived osteoclasts. Here we investigated the potential roles of p38 MAPKs, which are activated by growth factors and cytokines includ...

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Detalles Bibliográficos
Autores principales: Cong, Qian, Jia, Hao, Li, Ping, Qiu, Shoutao, Yeh, James, Wang, Yibin, Zhang, Zhen-Lin, Ao, Junping, Li, Baojie, Liu, Huijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382695/
https://www.ncbi.nlm.nih.gov/pubmed/28382965
http://dx.doi.org/10.1038/srep45964