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Gapped alignment of protein sequence motifs through Monte Carlo optimization of a hidden Markov model
BACKGROUND: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservation present in these protein sequences presumably are due to selective constraints maintaining important but unknown struc...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2004
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC538276/ https://www.ncbi.nlm.nih.gov/pubmed/15504234 http://dx.doi.org/10.1186/1471-2105-5-157 |