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Human T lymphotropic virus type-1 p30(II )alters cellular gene expression to selectively enhance signaling pathways that activate T lymphocytes

BACKGROUND: Human T-lymphotropic virus type-1 (HTLV-1) is a deltaretrovirus that causes adult T-cell leukemia/lymphoma and is implicated in a variety of lymphocyte-mediated disorders. HTLV-1 contains both regulatory and accessory genes in four pX open reading frames. pX ORF-II encodes two proteins,...

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Detalles Bibliográficos
Autores principales: Michael, Bindhu, Nair, Amrithraj M, Hiraragi, Hajime, Shen, Lei, Feuer, Gerold, Boris-Lawrie, Kathleen, Lairmore, Michael D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC538277/
https://www.ncbi.nlm.nih.gov/pubmed/15560845
http://dx.doi.org/10.1186/1742-4690-1-39