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Rosmarinic acid suppresses colonic inflammation in dextran sulphate sodium (DSS)-induced mice via dual inhibition of NF-κB and STAT3 activation

Ulcerative colitis (UC), a type of inflammatory bowel disease (IBD), is a chronic inflammatory disorder of the colon. Although UC is generally treated with anti-inflammatory drugs or immunosuppressants, most of these treatments often prove to be inadequate. Rosmarinic acid (RA) is a phenolic ester i...

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Detalles Bibliográficos
Autores principales: Jin, Bo-Ram, Chung, Kyung-Sook, Cheon, Se-Yun, Lee, Minho, Hwang, Soonjae, Noh Hwang, Sam, Rhee, Ki-Jong, An, Hyo-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382778/
https://www.ncbi.nlm.nih.gov/pubmed/28383063
http://dx.doi.org/10.1038/srep46252