Dual inhibiting OCT4 and AKT potently suppresses the propagation of human cancer cells

AKT serves as an epigenetic modulator that links epigenetic regulation to cell survival and proliferation while the epigenetic mediator OCT4 critically controls stem cell pluripotency and self-renewal. Emerging evidence indicated their complicated interplays in cancer cells and cancer stem cells (CS...

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Detalles Bibliográficos
Autores principales: Li, Wenxin, Zhou, Yanwen, Zhang, Xiaoqian, Yang, Ying, Dan, Songsong, Su, Tong, She, Shiqi, Dong, Weilai, Zhao, Qingwei, Jia, Jia, Yao, Hangping, Zheng, Min, Kang, Bo, Wang, Ying-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382782/
https://www.ncbi.nlm.nih.gov/pubmed/28383051
http://dx.doi.org/10.1038/srep46246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382782/
https://www.ncbi.nlm.nih.gov/pubmed/28383051
http://dx.doi.org/10.1038/srep46246

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