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Foxo3a induces motoneuron death through the Fas pathway in cooperation with JNK
BACKGROUND: Programmed cell death of motoneurons in the developing spinal cord is thought to be regulated through the availability of target-derived neurotrophic factors. When deprived of trophic support, embryonic spinal motoneurons in vitro over-express FasL, a ligand activating a Fas-mediated dea...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC538283/ https://www.ncbi.nlm.nih.gov/pubmed/15569384 http://dx.doi.org/10.1186/1471-2202-5-48 |